Home
Home   >   Projects   >   Axis 2

Axis 2 : Mitochondria-nucleus cross-talk

Five main aspects will be addressed:

1. mRNA sorting at the surface of mitochondria

Identification of all population of targeted mRNAs / Identification of cis-elements and trans-factors

2. RNA mitochondrial import

Deciphering RNA targeting and import mechanisms / Establishment of crystallographic structures of molecular complexes between imported RNAs and protein effectors

3. Mitochondrial targeting of proteins

Investigation of the import and processing of PPR proteins and mt-aaRS / Deciphering N-terminal sequence of imported proteins after maturation

4. Dual targeting of proteins

Determination of the multiple location of imported proteins in mitochondria and in chloropasts / Determination of the sub-organellar location of imported proteins

5. Manipulation of mitochondrial gene expression

Investigation of the mitochondrial genetic regulation and retrograde response by interfering with gene expression

>> Back to the general description of the project

Search & Find

Flux RSS

Feb 23 2023

Journal of Mitochondria, Plastids and Endosymbiosis (JMPE) is dedicated to serving the biology...

RSS Feed

From June 8, 2023 until June 10, 2023
Riva del Garda, Italy