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Publications before 2012

2011

  • Blaise M., Frechin M., Olieric V., Charron C., Sauter C., Lorber B., Roy H. and Kern D. (2011).
    Crystal structure of the archaeal asparagine synthetase. Interrelation with aspartyl- and asparaginyl-tRNA synthetases
    J Mol Biol 412(3), 437-452. Abstract
  • Bonnefond L., Schellenberger P., Basquin J., Demangeat G., Ritzenthaler C., Chênevert R., Balg C., Frugier M., Rudinger-Thirion J., Giegé R., Lorber B. and Sauter C. (2011).
    Exploiting protein engineering and crystal polymorphism for successful X-ray structure determination.
    Crystal Growth & Design 11(10), 4334-4343. Abstract
  • Huot J.L., Fischer F., Corbeil J., Madore E., Lorber B., Diss G., Hendrickson T., Kern D. and Lapointe J. (2011).
    Gln-tRNAGln synthesus is a dynamic transamidosome from Helicobacter pylori, where GluRS2 hydrolyses excess Glu-tRNAGln.
    Nucleic Acids Res 39(21), 9306-9315. Abstract
  • Jester B.C., Drillien R., Ruff, M. and Florentz C. (2011).
    Using Vaccinia's innate ability to introduce DNA into mammalian cells for production of recombinant proteins.
    J Biotechnol 156(3), 211-213. Abstract
  • Messmer M., Florentz C., Schwenzer H., Scheper G.C., van der Knaap M.S., Marechal-Drouard L. and Sissler M. (2011).
    A human pathology-related mutation prevents import of an aminoacyl-tRNA synthetase into mitochondria.
    Biochem J 433(3), 441-446. Abstract
  • Schellenberger P., Demangeat G., Lemaire O., Ritzenthaler C., Bergdoll M., Olieric V., Sauter C. and Lorber B. (2011).
    Strategies for the crystallization of viruses: Using phase diagrams and gels to produce 3D crystals of Grapevine fanleaf virus.
    J Struct Biol 174(2), 344-351. Abstract 
  • Schellenberger P., Sauter C., Lorber B., Bron P., Trapani S., Bergdoll M., Marmonier A., Schmitt-Kelchinger C., Lemaire O., Demangeat G. and Ritzenthaler C. (2011).
    Structural insights into viral determinants of nematode mediated grapevine fanleaf virus transmission.
    PLoS Pathogens 7(5), e1002034. Abstract 

2010

  • Bouakaze C., Eschbach J., Fouquerel E., Gasser I., Kieffer E., Krieger S., Milosevic S., Saandi T., Florentz C., Maréchal-Drouard L.and Labouesse M. (2010).
    "OpenLAB" : a two-hour PCR-based practical for high school studients.
    Biochemistry and Molecular Biology Education 38(5), 296-302. Abstract
  • Giegé, R. and Sauter C. (2010).
    Biocrystallography : past, present, future.
    HFSP J 4(3-4), 109-121. Abstract
  • Marquette R., Lorber B. and Bechinger B. (2010).
    Reversible liposome association induced by LAH4 : A peptide with potent antimicrobial and nucleic acid transfection activities.
    Biophys J 98(11), 2544-2553. Abstract
  • Putz J., Giege R. and Florentz C. (2010).
    Diversity and similarity in the tRNA world: overall view and case study on malaria-related tRNAs.
    FEBS Lett 584(2), 350-358. Abstract

2009

  • Bailly M., Blaise M., Lorber B., Thirup S. and Kern D. (2009).
    Isolation, crystallization and preliminary X-ray analysis of the transamidosome, a ribonucleoprotein involved in asparagine formation.
    Acta Crystallogr Sect F Struct Biol Cryst Commun 65(Pt 6), 577-81. Abstract
  • Bour T., Akaddar A., Lorber B., Blais S., Balg C., Candolfi E. and Frugier M. (2009).
    Plasmodial aspartyl-tRNA synthetases and peculiarities in Plasmodium falciparum.
    J Biol Chem 284(28), 18893-903. Abstract
  • Dhouib K., Khan Malek C., Pfleging W., Gauthier-Manuel B., Duffait R., Thuillier G., Ferrigno R., Jacquamet L., Ohana J., Ferrer J.L., Theobald-Dietrich A., Giege R., Lorber B. and Sauter C. (2009).
    Microfluidic chips for the crystallization of biomacromolecules by counter-diffusion and on-chip crystal X-ray analysis.
    Lab Chip 9(10), 1412-21. Abstract
  • Florentz C. (2009).
    Organisation et expression des génomes des organites.
    In Biochemie Générale 11e Edition (Weil J.H., ed.). Dunod, Paris. Link
  • Juhling F., Morl M., Hartmann R.K., Sprinzl M., Stadler P.F. and Putz J. (2009).
    tRNAdb 2009: compilation of tRNA sequences and tRNA genes.
    Nucleic Acids Res 37, D159-62. Abstract
  • Lorber B., Sauter C., Theobald-Dietrich A., Moreno A., Schellenberger P., Robert M.C., Capelle B., Sanglier S., Potier N. and Giegé R. (2009).
    Crystal growth of proteins, nucleic acids, and viruses in gels.
    Prog Biophys Mol Biol 101(1-3), 13-25. Abstract
  • Messmer M., Blais S.P., Balg C., Chenevert R., Grenier L., Lague P., Sauter C., Sissler M., Giege R., Lapointe J. and Florentz C. (2009).
    Peculiar inhibition of human mitochondrial aspartyl-tRNA synthetase by adenylate analogs.
    Biochimie 91(5), 596-603. Abstract
  • Messmer M., Gaudry A., Sissler M. and Florentz C. (2009).
    Pathology-related mutation A7526G (A9G) helps in the understanding of the 3D structural core of human mitochondrial tRNA(Asp).
    RNA 15(8), 1462-8. Abstract
  • Messmer M., Putz J., Suzuki T., Sauter C., Sissler M. and Florentz C. (2009).
    Tertiary network in mammalian mitochondrial tRNAAsp revealed by solution probing and phylogeny.
    Nucleic Acids Res 37(20), 6881-95. Abstract
  • Sauter C., Balg C., Moreno A., Dhouib K., Théobald-Dietrich A., Chenevert R., Giegé R. and Lorber B.(2009).
    Agarose gel facilitates enzyme crystal soaking with a ligand analog
    J Appl Cryst 42, 279-283. Abstract

2008

  • Bailly M., Blaise M., Roy H., Deniziak M., Lorber B., Birck C., Becker H.D. and Kern D. (2008).
    tRNA-dependent asparagine formation in prokaryotes: Characterization, isolation and structural and functional analysis of a ribonucleoprotein particle generating Asn-tRNA(Asn).
    Methods 44(2), 146-163. Abstract
  • Blaise M., Olieric V., Sauter C., Lorber B., Roy B., Karmakar S., Banerjee R., Becker H.D. and Kern D. (2008)
    Crystal structure of Glutamyl-Queuosine tRNAAsp synthetase complexed with L-Glutamate : structural elements mediating tRNA-independent activation of glutamate and glutamylation of tRNAAsp anticodon.
    J Mol Biol 381(5), 1224-1237.Abstract
  • Bonnefond L., Florentz C., Giege R. and Rudinger-Thirion J. (2008).
    Decreased aminoacylation in pathology-related mutants of mitochondrial tRNATyr is associated with structural perturbations in tRNA architecture.
    RNA 14(4), 641-648. Abstract
  • Giegé R., Touzé E., Lorber B., Théobald-Dietrich A., Sauter C. (2008).
    Crystallogenesis trends of free and liganded aminoacyl-tRNA synthetases.
    Crystal Growth & Design 8(12), 4297-4306. Abstract
  • Lorber B. (2008).
    Virus and Protein Crystallization under Hypergravity.
    Crystal Growth & Design 8(8), 2964-2969. Abstract
  • Lorber B., Adrian M., Witz J., Erhardt M. and Harris J.R. (2008).
    Formation of two-dimensional crystals of icosahedral RNA viruses.
    Micron 39(4), 431-46. Abstract
  • Lorber B. and Witz J. (2008).
    An Investigation of the Crystallogenesis of an Icosahedral RNA Plant Virus with Solubility Phase Diagrams.
    Crystal Growth & Design 8(5), 1522-1529. Abstract
  • Sissler M., Lorber B., Messmer M., Schaller A., Putz J. and Florentz C. (2008).
    Handling mammalian mitochondrial tRNAs and aminoacyl-tRNA synthetases for functional and structural characterization.
    Methods 44(2), 176-189. Abstract

2007

  • Bailly M., Blaise M., Lorber B, Becker H. D. and Kern D. (2007)
    The transamidosome : a dynamic ribonucleoprotein particle dedicated to prokaryotic tRNA-dependent asparagine formation.
    Molecular Cell 28(2), 228-239 Abstract
  • Bonnefond L., Frugier M., Touze E., Lorber B., Florentz C., Giege R., Rudinger-Thirion J. and Sauter C. (2007).
    Tyrosyl-tRNA synthetase: the first crystallization of a human mitochondrial aminoacyl-tRNA synthetase.
    Acta Crystallogr Sect F Struct Biol Cryst Commun 63(Pt 4), 338-41. Abstract
  • Bonnefond L., Frugier M., Touze E., Lorber B., Florentz C., Giege R., Sauter C. and Rudinger-Thirion J. (2007).
    Crystal Structure of Human Mitochondrial Tyrosyl-tRNA Synthetase Reveals Common and Idiosyncratic Features.
    Structure 15(11), 1505-16. Abstract
  • Olieric V., Schreiber A., Lorber B. and Pütz J. (2007).
    From egg to crystal - A practical on purification, characterization, and crystallization of lysozyme for bachelor students.
    Biochemistry and Molecular Biology Education 35(4), 280-286. Abstract
  • Putz J., Dupuis B., Sissler M. and Florentz C. (2007).
    Mamit-tRNA, a database of mammalian mitochondrial tRNA primary and secondary structures.
    RNA 13(8), 1184-90. Abstract
  • Sauter C., Dhouib K. and Lorber B. (2007).
    From macrofluidies to microfluidies for the crystallization of biological macromolecules.
    Crystal Growth & Design 7(11), 2247-50. Abstract
  • Scheper G.C., van der Klok T., van Andel R.J., van Berkel C.G., Sissler M., Smet J., Muravina T.I., Serkov S.V., Uziel G., Bugiani M., Schiffmann R., Krageloh-Mann I., Smeitink J.A., Florentz C., Van Coster R., Pronk J.C. and van der Knaap M.S. (2007).
    Mitochondrial aspartyl-tRNA synthetase deficiency causes leukoencephalopathy with brain stem and spinal cord involvement and lactate elevation.
    Nat Genet 39(4), 534-9. Abstract 
  • Touzé R., Lorber B., Deniziak M., Becker H. D., Kern D., Giegé R. and Sauter C. (2007) 
    How much disorder can exist in well-diffracting crystals?
    Crystal Growth & Design 7(11), 2195-96. Abstract

2006

  • Fender, A., Sauter, C., Messmer, M., Putz, J., Giege, R., Florentz, C. & Sissler, M. (2006).
    Loss of a primordial identity element for a mammalian mitochondrial aminoacylation system.
    J Biol Chem. 281(23), 15980-6 Abstract

2005

  • Bonnefond L., Fender A., Rudinger-Thirion J., Giege R., Florentz C. and Sissler M. (2005).
    Toward the Full Set of Human Mitochondrial Aminoacyl-tRNA Synthetases: Characterization of AspRS and TyrRS.
    Biochemistry 44, 4805-16. Abstract
  • Sissler M., Puetz J., Fasiolo F. and Florentz C. (2005).
    Mitochondrial aminoacyl-tRNA synthetases.
    In The Aminoacyl-tRNA Synthetases ( Ibba M., Francklyn C. and Cusak S., eds.). Landes Biosciences. Full text

2004

  • Barends S., Rudinger-Thirion J., Florentz C., Giegé R., Pleij C.W. and Kraal B. (2004). 
    tRNA-like structure regulates translation of brome mosaic virus RNA.
    J. Virology. 78, 4003-4010. Abstract
  • Fender A., Geslain R., Eriani G., Giegé R., Sissler M. and Florentz C. (2004). 
    A yeast arginine specific tRNA is a remnant aspartate acceptor.
    Nucleic Acid Res. 32, 5076-5086. Abstract
  • Fender A., Sissler M., Florentz C. and Giegé R. (2004). 
    Functional idiosyncrasies of tRNA isoacceptors in cognate and noncognate aminoacylation systems. Biochimie 86, 21-29. Abstract
  • Levinger L., Oestereich I., Florentz C. and Mörl M. (2004). 
    A pathogenesis-associated mutation in human mitochondrial tRNALeu(UUR) leads to reduced 3'-end processing and CCA addition.
    J. Mol. Biol. 337, 535-544. Abstract
  • Sissler M., Helm M., Frugier M., Giegé R. and Florentz C. (2004). 
    Aminoacylation properties of pathology-related variants of human mitochondrial tRNALys variants.
    RNA 10, 841-853. Abstract
  • Sohm B., Sissler M., Park H., King M.P. and Florentz C. (2004). 
    Recognition of human mitochondrial tRNALeu(UUR) by its cognate leucyl-tRNA synthetase.
    J. Mol. Biol. 339, 17-29. Abstract
  • Levinger L., Mörl M. and Florentz C. (2004). 
    Mitochondrial tRNA 3' end metabolism and human disease.
    Nucleic Acid Res. 32, 5430-5441. Abstract

2003

  • Tryoen-Tóth P., Richert S., Sohm B., Mine M., Marsac C., Van Dorsselaer A., Leize E. and Florentz C. (2003). 
    Proteomic consequences of a human mitochondrial tRNA mutation beyond the frame of mitochondrial translation.
    J. Biol. Chem. 278, 24314-24323. Abstract
  • Sohm B., Frugier M., Brulé H., Olszak K., Przykorska A. and Florentz C. (2003). 
    Towards understanding human mitochondrial leucine aminoacylation identity.
    J. Mol. Biol. 328, 995-1010. Abstract
  • Levinger L., Giegé R. and Florentz C. (2003). 
    Pathology-related substitutions in human mitochondrial tRNAIle reduce precursor 3'-end processing efficiency in vitro.
    Nucleic Acids Res. 31, 1904-1912. Abstract
  • Florentz C., Sohm B., Tryoen-Tóth P., Pütz J. and Sissler M. (2003). 
    Human mitochondrial tRNAs in health and disease.
    CMLS 60, 1356-1375. Abstract
  • Florentz C. and Sissler M. (2003). 
    Mitochondrial tRNA aminoacylation and human diseases.
    in Translation mechanisms (Lapointe J. and Brakier-Gingras L., eds.),
  • Du W., Marsac C., kruschina M., Ortigao F. and Florentz C. (2003). 
    Functionalized self-assembled monolayer on gold for detection of human mitochondrial tRNA gene mutations.
    Analytical Biochemistry 322, 14-25. Abstract

2002

  • Rabilloud T., Strub J.M., Carte N., Luche S., Van Dorsselaer A., Lunardi J., Giegé R. and Florentz C. (2002). 
    Comparative proteomics as new tool for exploring human mitochondrial tRNA disorders.
    Biochemistry 41, 144-150. Abstract
  • Florentz C. (2002). 
    Molecular investigations on tRNAs involved in human mitochondrial disorders.
    Biocscience Reports 22, 81-98. Abstract
  • Walter F., Pütz J., Giegé R. and Westhof E. (2002).
    Binding of tobramycin leads to conformational changes in yeast tRNAAsp and inhibition of aminoacylation.
    EMBO J. 21, 760-768. Abstract

2001

  • Florentz C., Pütz J., Sissler M. and Giegé R. (2001).
    ARNt mitochondriaux humains.
    in pp. 71-86. Editions scientifiques et médicales Elsevier SAS,
  • Florentz C. and Sissler M. (2001) 
    Disease-related versus polymorphic mutations in human mitochondrial tRNAs: where is the difference?
    EMBO Reports 2, 481-486. Abstract
  • Fechter P., Rudinger-Thirion J., Florentz C. and Giegé R. (2001). 
    Novel features in the tRNA-like world of plant viral RNAs.
    Cellular Mol. Life Sciences 58, 1547-1561. Abstract
  • Giege R., Helm M. and Florentz C. (2001). 
    Classical and novel chemical tools for RNA structure probing

    In RNA (Soll D., Nishimura S. and Moore P., eds.) pp. 71-88. Pergamon. Link

2000

  • Helm M., Brulé H., Friede D., Giegé R., Pütz J. and Florentz C. (2000). 
    Search for characteristic structural features of mammalian mitochondrial tRNAs.
    RNA 6, 1356-1379. Abstract
  • Wientges J., Pütz J., Giegé R., Florentz C. and Schwienhorst A. (2000). 
    Selection of viral RNA-derived tRNA-like structures with improved valylation activities.
    Biochemistry 39, 6207-6218. Abstract

Before 2000

  • Wolfson A.D., Khvorova A.M., Sauter C., Florentz C. and Giegé R. (1999). 
    Mimics of yeast tRNAAsp and their recognition by aspartyl-tRNA synthetase.
    Biochemistry 38, 11926-11932. Abstract
  • Vlassov A.V., Helm M., Naumov V.A., Breusov A.A., Buneva V.N., Florentz C., Giegé R. and Nevinskii G.A. (1999). 
    Features of tRNA hydrolysis by autoantibodies from blood serum of patients with certain autoimmune and virus diseases. 
    Mol. Biol. (Mosk) 33, 866-872. Abstract
  • Martinis S.A., Plateau P., Cavarelli J. and Florentz C. (1999). 
    Aminoacyl-tRNA synthetases: a new image for a classical family. 
    Biochimie 81, 683-700. Abstract
  • Martinis S.A., Plateau P., Cavarelli J. and Florentz C. (1999). 
    Aminoacyl-tRNA synthetases: a family of expending functions. 
    EMBO J. 18, 4591-4596. Abstract
  • Madore E., Florentz C., Giegé R., Sekine S.-i., Yokoyama S. and Lapointe J. (1999). 
    Effect of modified nucleotides on Escherichia coli tRNAGlu structure and on its aminoacylation by glutamyl-tRNA synthetase; predominant and distinct roles of the mnm5 and s2 modifications of U34. 
    Eur. J. Biochem. 266, 1128-1135. Abstract
  • Madore E., Florentz C., Giegé R. and Lapointe J. (1999). 
    Magnesium-dependent alternate foldings of active and inactive Escherichia coli tRNAGlu revealed by chemical probing. 
    Nucleic Acids Res. 27, 3583-3588. Abstract
  • Helm M., Giegé R. and Florentz C. (1999). 
    A Watson-Crick base-pair disrupting methyl group (m1A9) is sufficient for cloverleaf folding of human mitochondrial tRNALys. 
    Biochemistry 38, 13338-13346. Abstract
  • Helm M., Florentz C., Chomyn A. and Attardi G. (1999). 
    Search for differences in post-transcriptional modification patterns of mitochondrial DNA-encoded wild-type and mutant human tRNALys and tRNALeu(UUR). 
    Nucleic Acids Res. 27, 756-763. Abstract
  • Helm M., Brulé H., Giegé R. and Florentz C. (1999). 
    More mistakes by T7 RNA polymerase at the 5'-ends of in vitro transcribed RNAs. 
    RNA 5, 618-621. Abstract
  • Giegé R., Helm M. and Florentz C. (1999). 
    Chemical and enzymatic probing of RNA structure. 
    In Comprehensive Natural Product Chemistry: Prebiotic Chemistry, Molecular Fossils, Nucleosides, and RNA (Soll D., Nishimura S. and Moore P., eds.), Vol. 6, pp. 63-80. Pergamon, Oxford.
  • Florentz C., Brulé H., Helm M. and Giegé R. (1999). 
    Structural studies of human mitochondrial tRNAs. 
    in Mitochondrial Diseases (Lestienne P., ed.)
  • Brulé H., Grosjean H., Giegé R. and Florentz C. (1998). 
    A pseudoknotted tRNA variant is a substrate for tRNA (cytosine-5)-methyltransferase from Xenopus laevis. 
    Biochimie 80, 1-9. Abstract
  • Brulé H., Holmes W.M., Keith G., Giegé R. and Florentz C. (1998). 
    Effect of a mutation in the anticodon of human mitochondrial tRNAPro on its post-transcriptional modification pattern.
    Nucleic Acids Res. 26, 537-543. Abstract
  • Degoul F., Brulé H., Cepanec C., Helm M., Marsac C., Leroux J.-P., Giegé R. and Florentz C. (1998).
    Isoleucylation properties of native human mitochondrial tRNAIle and tRNAIle transcripts. Implications for cardiomyopathy-related point mutations (4269, 4317) in the tRNAIle gene. 
    Hum. Mol. Gen. 7, 347-354. Abstract
  • Giegé R., Sissler M. and Florentz C. (1998). 
    Universal rules and idiosyncratic features in tRNA identity. 
    Nucleic Acids Res. 26, 5017-5035. Abstract
  • Helm M., Brulé H., Degoul F., Cepanec C., Leroux J.-P., Giegé R. and Florentz C. (1998). 
    The presence of modified nucleotides is required for cloverleaf folding of a human mitochondrial tRNA. 
    Nucleic Acids Res. 26, 1636-1643. Abstract
  • Sissler M., Giegé R. and Florentz C. (1998). 
    The tRNA sequence context defines the mechanistic routes by which yeast arginyl-tRNA synthetase charges tRNA. 
    RNA 4, 647-657. Abstract
  • Vlassov A., Florentz C., Helm M., Naumov V., Buneva V., Nevinsky G. and Giegé R. (1998). 
    Characterization and selectivity of catalytic antibodies from human serum with RNase activity. 
    Nucleic Acids Res. 26, 5243-5250. Abstract
  • Pütz J., Wientges J., Sissler M., Giegé R., Florentz C. and Schwienhorst A. (1997). 
    Rapid selection of aminoacyl-tRNAs based on biotinylation of ?-NH2 group of charged amino acids. 
    Nucleic Acids Res 25, 1862-1863. Abstract
  • Becker H.F., Motorin Y., Sissler M., Florentz C. and Grosjean H. (1997). 
    Major identity determinants for enzymatic formation of ribothymidine and pseudouridine in the T?-loop of yeast tRNAs.
    J. Mol. Biol. 274, 505-518. Abstract
  • Sissler M., Eriani G., Martin F., Giegé R. and Florentz C. (1997). 
    Mirror image alternative interaction patterns of the same tRNA with either class I arginyl-tRNA
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From October 9, 2017 until October 13, 2017
Brindisi, Italy
From October 9, 2017 until October 13, 2017
Brindisi, Italy